This relatively brief (7-day) history of oral MA is sufficient to induce some signs of anxiety-like behavior in both male and female mice, a deficit in reversal learning in female mice, and a number of sex-selective changes in the glutamate receptor expression and ERK/CaMKII activation within the vPFC, dPFC, hippocampus, and amygdala. Here, CAMK2G is linked to Anxiety.