We further observed the expression pattern of YTHDF1 in different diseases, as shown in Figure 1C. Compared with normal tissues, YTHDF1 was significantly up-regulated in 26 diseases, including breast cancer, and significantly down-regulated in acute myeloid leukemia (LAML) and thyroid cancer (THCA). The gene discussed is YTHDF1; the disease is acute myeloid leukemia.