CGAS and Aicardi-Goutieres syndrome: For example, an overactive cGAS/STING signaling pathway is associated with different autoinflammatory and autoimmune diseases, such as ataxia–telangiectasia (AT), Aicardi–Goutières syndrome (AGS), and STING-associated vasculopathy with onset in infancy (SAVI), erosive inflammatory arthritis (EIA), and several other inflammatory diseases, as discussed in detail elsewhere [79,110,155].