In a review article, Jankovic et al. [70] summarize the most relevant gene polymorphisms of ALR2, ACE, APOE, MTHFR, NOS3, VEGF, GPx-1, and CAT genes and the epigenomics (DNA methylation, miRNA, long non-coding RNA, and post-translational histone modifications) of diabetic neuropathy. Here, AKR1B1 is linked to diabetic neuropathy.