CARD11 was detected as a prognostic marker, with high expression associated to poor OS in the TCGA UVM dataset; in particular, metastatic patients had higher expression of this gene [31]; however, the MGS based on a larger dataset [17] assigned a protective effect to this gene, probably due to a set of patients with limited survival, metastatic disease and low CARD11 expression (Figures S2 and S3). The gene discussed is CARD11; the disease is metastatic neoplasm.