SQSTM1 and hepatocellular carcinoma: The gene profiling of sorafenib-induced ferroptosis showed that NAD(P)H quinone dehydrogenase 1, hemeoxigenase 1, ferritin heavy chain 1 and metallothionein 1G were involved, and the knockdown of these genes and p62 sensitized HCC to ferroptosis upon sorafenib and erastin treatment [77].