These results agree with previous in vitro studies conducted with different EP extracts on systemic inflammatory models [14,23,24,25,26], as well as few in vivo studies that reported anti-inflammatory activity (reducing IL-6, PGE2, and oxidative stress level, among others) in acetic acid-induced ulcerative colitis in rats [21], potassium dichromate-induced nephrotoxicity in rats [20], and in renal tissues of LPS-treated mice [47]. The gene discussed is IL6; the disease is ulcerative colitis.