EWSR1::BEND2 fusions are recurrent in a specific subtype of astroblastoma that is closely related to ‘astroblastoma, MN1-altered′, an entity that harbors MN1 GF with BEND2 as the typical partner, but they are slightly different in their methylation profile [39,40,41,42,43,44]. Here, BEND2 is linked to astroblastoma.