Conversely, a significant association between a higher abundance of Akkermansia, Enterococcus, Clostridiales, Ruminococcaceae, Faecalibacterium, and Bifidobacterium and an improved response to PDL1 therapy in cancers such as lung, renal, and melanoma has been found [183,185,186,187,188]. This evidence concerns the gene CD274 and cancer.