miR-3473b could be responsible for the regulation of pro-inflammatory mediators by targeting TREM2/UNC51-like kinase-1 (ULK1) expression to control the role of autophagy in the cause of inflammation in PD, implying that mir-3473b could be a feasible therapeutic target to manage the inflammatory response in PD [216]. This evidence concerns the gene ULK1 and Parkinson disease.