During EMT, cancer cells lose epithelial specific biomarkers (i.e., E-cadherin, cluster of differentiation CD44v variant isoform), while acquiring mesenchymal biomarkers (i.e., N-cadherin, fibronectin (FNT), vimentin (VIM), smooth muscle actin (α-SMA), β-catenin (CTNNB), CD44s standard isoform) [275]. The gene discussed is VIM; the disease is cancer.