They showed a prolonged duration of anxiety behavior and upregulation of cFos co-labeling in the calbindin1 + glutamatergic neurons in the ventral hippocampus CA1 and in the DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of M(r) 32 kDa) + glutamatergic neurons in the posterior basolateral amygdala after an optogenetic stimulation in the ventral dentate gyrus of GR overexpression mice [23]. Here, NR3C1 is linked to Anxiety.