In addition, the members of the miR548 family suppress the growth, movement, and infiltration of different types of cells, such as glioma, melanoma, and osteoblast-like cells, by reducing the expression of c-Myb [48], HMGB1 [49] MAFB, and STAT1 [50], genes already reported as being associated with AD and neuroinflammation [51,52,53,54]. The gene discussed is HMGB1; the disease is central nervous system cancer.