We conducted a secondary analysis of the psychological symptom burden in the LIMBIC CENC cohort to evaluate whether the levels of the four serum lncRNAs (VLDLR-AS1, MALAT1, NEAT1, GAS5) correlate to symptom burden (such as cognition, memory, depression or PTSD) after rmTBI. The gene discussed is VLDLR; the disease is depressive disorder.