High levels of CD123 expression were detected in up to 100% of the samples analyzed through flow cytometry, not just in BPDCN but also in acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), hairy cell leukemia (HCL), myelodysplastic syndromes (MDS), and chronic eosinophilic leukemia [37,38,39,40]. This evidence concerns the gene IL3RA and hairy cell leukemia.