We analyzed whether the polymorphism was correlated with the cytokine expression of IL1β, IFNα2, IFNγ, TNF-α, IL-33, IL12p70, MCP-1, IL-6, IL-10, IL-17a, IL-18, or IL-23 to further investigate the effect of the polymorphism in sepsis patients. This evidence concerns the gene IL18 and Sepsis.