By contrast, neutrophils and B cells were mainly located at the tumor margin (neutrophils: core 1.08% vs. margin 6.69%, p = 0.03; B cells: core 0.07% vs. margin 2.25%; p = 0.85) (Figure 2F,G), whereas no difference was found in DC and CD4+ T cell distribution between the core and margin of the tumor (DCs: core 5.89% vs. margin 6.93%, p = 1; CD4+ T cells: core 3.49% vs. margin 3.15%, p = 1). This evidence concerns the gene CD4 and neoplasm.