STAT3 and fibrosis: To further evaluate the anti-fibrotic efficacy of STAT3 decoy ODN in vivo, DDC-induced fibrosis mouse model was treated with fluorescein (FITC)-labeled STAT3 decoy ODN (STAT3 decoy ODN-treated mice with 0.1% DDC-supplemented diet (DDC + STAT3 mice)) (Figure 4a).