Moreover, the GRF genes, which encode growth-regulating factor proteins, were potentially regulated by novel_circ_0000150 and novel_circ_0000403 in the IR-TN1-BPH group, revealing a possible role of OsmiR396 in mediating the compatible and incompatible interactions between rice varieties and BPH populations. This evidence concerns the gene GHRH and benign prostatic hyperplasia.