CRP and rheumatoid arthritis: This has been addressed within the VA RA cohort previously, where after considering peak life BMI, current weight, and rate of annual weight loss in patients with RA, it was observed that a lower current weight and rate of weight loss were associated with greater mortality, and the latter was in a dose-dependent fashion where greater weight loss/year was associated with greater mortality, even after adjustment for RA disease activity parameters CRP and HAQ.