NOS2 and intestinal disorder: Gastric and intestinal ulcers induced by diclofenac (50 mg/kg) have been normalized using RJ at a dose of 150 mg/kg or 300 mg/kg via the increase of prostaglandin-2 (PGE-2) and COX-2 in the stomach tissues of mice, as well as reducing myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS) [71].