The same study also showed that the inhibition of miR-145-5p in asthmatic mice significantly reduced the development of airway hyperresponsiveness (reduced the number of both mucus-producing cells and eosinophils present in the airways) by the reduction in the production of IL-15 and IL-13 from antigen-specific Th2 cells; these effects were comparable with dexamethasone treatment [56]. Here, IL13 is linked to airway hyperresponsiveness.