IL5 and asthma: According to the above study, in a miR-155 KO mouse model of asthma, it was shown that a lack of miR-155 promotes a reduction in Th2 cells number and cytokines IL-4, IL-5, and IL-13, resulting in the decrease in eosinophil-mediated inflammation and mucus hypersecretion in the lung compared to wild-type asthmatic mice (Figure 2b) [87].