Likewise, in children with mild-to-moderate and severe asthma, it was observed that miR-34a correlated negatively with function lung parameters (FEV1FVC%pred and FEF2575%pred) [102], and with proinflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-17) in children with remissive asthma and exacerbated asthma [103]. This evidence concerns the gene TNF and asthma.