The following direct correlations were found: strong (leg salvage at 12 months vs. survival at 12 months, and healing at 12 months vs. leg salvage at 12 months), moderate (hemodialysis vs. renal failure, angiosome no. vs. wound PTA, and angiosome no. vs. wound ATA), and weak (diabetes insulin vs. sex, and angiosome no. vs. leg salvage at 12 months). This evidence concerns the gene INS and acute kidney injury.