Other studies have supported this, with one showing β2GPI immune complexes induced thrombosis and thrombocytopenia in a transgenic mouse model with humanised FcɣRIIa [61], as well as FcɣRIIa-dependence of platelet hyperreactivity demonstrated ex vivo using both aβ2GPI and anti-prothrombin antibodies (a non-criteria aPL) [62,63]. This evidence concerns the gene APOH and Venous thrombosis.