A noteworthy illustration is that over 11% of the samples exhibit the DQA1*05:01 ~ DQB1*02:01 haplotype, which has implications not only for celiac disease risk but also demonstrates varying risk levels based on the presence of the alleles DRB3*01:01:02 or DRB3*02:02:0167. This evidence concerns the gene HLA-DQA1 and celiac disease.