GO and GSEA of SDF-1ɑ revealed that the genes enriched in the GO enrichment analysis were involved mainly in channel activity, passive transmembrane transporter protein activity, ion channel activity, glycosaminoglycan binding, and structural components of the extracellular matrix, while the genes enriched in the GSEA were involved mainly in allografts, extracellular matrix receptor action, and the leishmaniasis pathway. This evidence concerns the gene CXCL12 and leishmaniasis.