To further confirm TYRP1 CAR selectivity, we assessed the cytotoxicity and cytokine release upon co-culture with a panel of non-melanoma TYRP1neg cell lines (A549 lung adenocarcinoma as well as UPS03 and UPS04 undifferentiated pleomorphic sarcoma). The gene discussed is TYRP1; the disease is undifferentiated pleomorphic sarcoma.