Finally, we measured the TYRP1 protein level by immunohistochemistry in metastatic lesions of cutaneous (n = 11), acral (n = 10), mucosal (n = 6), and uveal (n = 11) melanoma and showed that a significant subset of the patients analyzed presented high and homogeneous TYRP1 expression (Fig. 1g, h and Supplementary Fig. 1a). The gene discussed is TYRP1; the disease is melanoma.