Regression analyses were conducted to examine the independent associations of neuropathological measures for VaD, CAA, amyloid score, TDP-43, synuclein, AD-tau, and AGD-tau with AD-related molecules (Table 4 [FA], and Additional file 1: Tables S5 [TBS] and S6 [TBSX]). The gene discussed is MAPT; the disease is Alzheimer disease.