AD-tau pathology was positively associated with the levels of insoluble Aβ42 (FA: β = 12.27, p < 0.001) and pTau181 (FA: β = 0.41, p = 0.001), as well as negatively associated with levels of detergent-soluble tTau (TBSX: β = -0.23, p < 0.001), in full multivariable analysis. This evidence concerns the gene MAPT and Alzheimer disease.