TLR3 and acute lymphoblastic leukemia: Interestingly, ERV-GFP expression leads to increased incidences of T cell acute lymphatic leukemia (T-ALL) with a shift from late (in Tlr3−/−Tlr7−/−Tlr9−/− mice) to early onset in EGT-315 Tlr3−/−Tlr7−/−Tlr9−/− mice (Fig. S1a, c).