We observed alpha diversities of TCR α and β were significantly decreased in JIA patients compared with controls (PTCRα = 9.60 × 10−04 and PTCRβ = 1.36 × 10−02), which indicates that the clonotypic diversities of TCRs were reduced in the JIA group (Fig. 5A). Here, PTCRA is linked to juvenile idiopathic arthritis.