TGFBR2 and nephrolithiasis: Further, genes associated with kidney stones, including CG31674 (0.068, p = 0.00013), Vha55 (0.25, p = 0.012), MFS2 (0.0021, p = 0.00033), and Prestin (0.36, p = 0.011), were down-regulated, and the Aquaporin genes Eglp2 (0.011, p = 0.0029) and Eglp4 (0.0035, p = 0.00054) were also down-regulated (Fig. 3F, Supplementary Fig. 4E).