Interestingly, myotubularin-related protein 6 (MTMR6) p.A599T was also identified in large intestine cancer, while cellular tumor antigen p53 (TP53) p.P72R was confirmed in multiple cancers affecting the bone, skin, meninges, and large intestine (Additional file 1: Fig. S3b). This evidence concerns the gene MTMR6 and colorectal cancer.