With recent advancements in the technology available to the vector-borne disease community, such as Clustered Regularly Interspaced Palindromic Repeats (CRISPR) in ticks [30], and ectopic expression in tick cells [31], future work can aim to unravel Rab27’s exact mechanism of action as well as its interaction with important tick-borne pathogens, such as A. phagocytophilum [32]. This evidence concerns the gene RAB27A and vector-borne disease.