NPPB and acute kidney injury: ROC analysis regarding the endpoint AKI showed an AUC of 0.84 for IL-6 and 0.81 for bio-ADM(Fig. 3), therefore having the highest discriminatory capability of all other biomarkers in this comparison like hsTnT, NT-proBNP and creatinine (0.80, 0.76 and 0.75).