MYD88 and non-Hodgkin lymphoma: In another study by Zhou et al, the most frequently mutated genes in their patient cohort diagnosed with non-Hodgkin lymphoma were PIM1 (77.27%), MYD88 (63.64%), CD79B (59.09%), and KMT2D (50.0%).[15] In our study, PIM1 p.G28A mutation was observed in 2% of NHL cases and 1 of 4 (25%) THRLBCL cases.