Use of the biologic agent infliximab: Infliximab is a monoclonal antibody that targets tumor necrosis factor-alpha and has been widely used to treat IBD such as UC and CD.[13] The use of infliximab: Infliximab is a monoclonal antibody that targets tumor necrosis factor-alpha and has been widely used for the treatment of IBD such as UC and CD.[14]. This evidence concerns the gene TNF and inflammatory bowel disease.