Leveraging The Cancer Genome Atlas (TCGA) datasets, we investigated NR4A1 expression in melanoma patients and identified a negative correlation between NR4A1 and genes involved in the antitumor immune responses, including IFNγ (interferon γ), GZMB (granzyme B), and PRF1 (perforin) (Fig. S1, A–C). This evidence concerns the gene NR4A1 and melanoma.