Figure 5B demonstrates that IH-induced high MVD levels were partly reversed by TSA or miR-138 mimic administration. IH contributed to low apoptosis levels, as evident from the reduced levels of BAX and Caspase-3, and TUNEL levels in the IH group; both TSA and miR-138 increased the apoptosis under IH condition (Figure 5C, 5D). Here, CASP3 is linked to isolated hemihyperplasia.