After Lasso regression analysis and multifactorial Cox regression analysis (Figure 2B, 2C), 5 lncRNAs (FAM225B, ZNF503-AS1, SPINT1-AS1, WWC2-AS2, LINC01338) emerged as independent risk factors for the prognosis of renal clear cell carcinoma. This evidence concerns the gene WWC2 and clear cell renal carcinoma.