The lncRNAs include HBV Enhancer-Induced lncRNA (HEIH), HCC Up-Regulated Long Non-Coding RNA (HULC), Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1), UC001kfo.1, Dreh, Upregulation of these lncRNAs promotes the progression of HCC for HBV infected patients. The gene discussed is MALAT1; the disease is hepatocellular carcinoma.