PTEN and liver cancer: These studies primarily focus on which pathways miR-3682-3p regulates in liver cancer, including the RAS-MEK1/2-ERK1/2 pathway (18), FOXO3/PI3K/AKT/c-Myc pathway (19), miR-3682-3p-PHLDA1-FAS pathway (20), and PTEN/PI3K/AKT/beta-catenin pathway (21).