TRPM3 and Neurodevelopmental delay: Recently, de novo missense mutations in TRPM3 have been found to underlie a spectrum of neurological disorders, referred to as TRPM3-related neurodevelopmental disorder (TRPM3-NDD), that includes congenital hypotonia, developmental delay, intellectual disability, seizures, musculoskeletal, and ophthalmological findings [49,50,51].