In pancreatic and colorectal cancers, SCs migrate to tumor cells, but not to benign cells, via the NGF-neurotrophic receptor tyrosine kinase 1 (NTRK1/TrkA)–nerve growth factor receptor (NGFR/p75NTR) axis before tumor cells initiate migration towards the peripheral nerves, likely providing a pathway for tumor cell invasion [67,69]. This evidence concerns the gene NTRK1 and colorectal cancer.