Additionally, the upregulation of Clec7a, encoding the pathogen recognition receptor Clec7a, in microglia has recently been shown to promote neuroinflammation in a mouse model of Parkinson’s disease [54], while the roles of Cst7, Itgax, and Lilrb4 in relation to Parkinson’s disease remain to be further investigated. The gene discussed is ITGAX; the disease is Parkinson disease.