UCHL1 and neoplasm: Genes such as Neuroligin-4X (NLGN4X), involved in the development and maintenance of synapse functioning, and neural protein or enzyme markers such as Doublecortin (DCX) and Ubiquitin C-Terminal Hydrolase-L1 (UCHL-1) were expressed in tumor microenvironments which serve to emphasize the neural involvement in BPDCN [6,25].