To have an overview of current MRGPRX2 research in relation to allergic diseases, we conducted a literature search in PubMed using key words “atopic dermatitis” or “urticaria” and “MRGPRX2”, following the search string as described in Figure 1, however, additionally filtering only for the latest research, from 2020 until 2023. The gene discussed is MRGPRX2; the disease is atopic eczema.