IDH1 and central nervous system cancer: We further analyzed the transcriptional differences between the IDH-mutant and IDH-WT mouse gliomas by performing GSEA using the Barres murine brain transcriptome database [46] to create cell-type-specific gene sets for astrocytes, oligodendrocytes, neurons, OPCs, newly formed oligodendrocytes, myelinating oligodendrocytes, microglia, and endothelia for analysis.