SELL and obesity due to melanocortin 4 receptor deficiency: However, using unsupervised clustering analysis, we identified an NK-cell phenotype related to obesity, with clusters of CD56bright immature NK, CD56bright CD62L+KIR2D+ (double positive) transitioning NK, and CD56dimCD16+ double-positive NKs significantly decreased in NGT obese women compared to non-obese, the latter population being also decreased in GDM non-obese (Fig. 2F; Supplementary Fig. S5).