IL‐38 was shown to inhibit the maturation of DCs in atherosclerosis by blocking the NF‐κB pathway, thereby increasing the expression of the anti‐inflammatory cytokine IL‐10 and reducing the expression of the pro‐inflammatory cytokines IL‐23, TNF‐α, and IFN‐γ expression.126. The gene discussed is NFKB1; the disease is atherosclerosis.