TFRC and nutritional disorder: Our results showed that Sev dramatically downregulated the FtH, FtL expression, and upregulated the TfR1 expression in hippocampus and/or cortex, indicating that Sev also caused the iron deficiency in the cortex and hippocampus as shown in Figure 4A–D which was consistent with Perl's iron‐staining results (Figure 4E,F).