The results showed that Sev significantly decreased the expression of FtH (t(4) = 5.333, p = 0.0060, cortex; t(4) = 6.770, p = 0.0064, hippocampus) and FtL (t(4) = 5.233, p = 0.0064, cortex) but increased the expression of TfR1(t(4) = 9.852, p < 0.001, cortex; t(4) = 17.12, p < 0.001, hippocampus), meaning that Sev caused the iron deficiency in both tissues as shown in Figure 4A–D. The gene discussed is TFRC; the disease is Iron deficiency anemia.